| Darlene | 1 | Human |
| Darwin the Devil | 1 | Human |
| Dassa Ben-Ami | 6 | Human |
| Dave | 1 | Ghoul |
| Davenport | 8 | Mr. Handy |
| David Thorpe | 68 | Scorched |
| Davie Taylor | 66 | Human |
| Day o' Work Station | 5 | Protectron |
| Daz | 8 | Mr. Handy |
| Deactivated Liberator | 10 | Liberator |
| Dead Responder | 1 | Human |
| Deadly Angler | 100 | Angler |
| Deadly Bloatfly | 90 | Bloatfly |
| Deadly Bloodbug | 85 | Bloodbug |
| Deadly Cave Cricket | 100 | Cave Cricket |
| Deadly Feral Ghoul | 100 | Feral Ghoul |
| Deadly Floater Flamer | 73 | Floater |
| Deadly Floater Freezer | 73 | Floater |
| Deadly Floater Gnasher | 73 | Floater |
| Deadly Glowing Ant | 95 | Radant |
| Deadly Glowing One | 100 | Feral Ghoul |
| Deadly Honey Beast | 100 | Honey Beast |
| Deadly Mirelurk | 100 | Mirelurk |
| Deadly Mirelurk Hunter | 100 | Mirelurk Hunter |
| Deadly Mirelurk King | 100 | Mirelurk King |
| Deadly Mole Miner | 95 | Mole Miner |
| Deadly Mole Rat | 95 | Mole Rat |
| Deadly Mutant Hound | 95 | FEV Hound |
| Deadly Radscorpion | 100 | Radscorpion |
| Deadly Radtoad | 100 | Radtoad |
| Deadly Soldier Ant | 80 | Radant |
| Deadly Stingwing | 100 | Stingwing |
| Deadly Wolf | 100 | Wolf |
| Deadly Yao Guai | 100 | Yao Guai |
| Deathclaw | 21 | Deathclaw |
| Deathclaw | 15 | Deathclaw |
| Deathclaw | 15 | Deathclaw |
| Deathclaw Consort | 47 | Deathclaw |
| Deathclaw Handler | 75 | Human |
| Deathclaw Handler | 60 | Human |
| Deathclaw Matriarch | 41 | Deathclaw |
| Deathclaw Matriarch | 77 | Deathclaw |
| Deathclaw Matriarch | 77 | Deathclaw |
| Deathklaus | 66 | Human |
| Deathskull Radscorpion | 64 | Radscorpion |
| Debug EyeBot | 1 | EyeBot |
| Decaying Feral Ghoul | 72 | Feral Ghoul |
| Default One Star Target | 100 | Human |
| Default Three Star PA Target | 100 | Human |
| Default Three Star Target | 100 | Human |