| Sugar | 0.25 | 6 | 3 | |
| Sugar Bombs | 0.5 | 8 | 4 | |
| Sugar Bombs | 0.5 | 9 | 3 | |
| Sugar-Free Nukashine | 1 | 0 | 9 | Addictive |
| Summer Filet | 0.1 | 8 | 3 | |
| Sunday Shine | 1.2 | 10 | 9 | Addictive |
| Sunscream | 0.5 | 5 | 4 | |
| Sunset Sarsaparilla | 1 | 15 | 4 | |
| Sunshine Oil | 1 | 6 | 3 | |
| Super Chem MK I | 0.1 | 0 | 4 | |
| Super Chem MK II | 0.1 | 0 | 7 | |
| Super Chem MK III | 0.1 | 0 | 7 | |
| SuperChem | 0.1 | 0 | 7 | |
| Surly's Buffout | 0 | 0 | 7 | Addictive |
| Survival Syringe | 0.1 | 0 | 6 | |
| Swamp Plant | 0.5 | 12 | 3 | |
| Swamp Tofu | 0.5 | 12 | 4 | |
| Swamp Tofu Soup | 0.5 | 22 | 5 | |
| Sweet Blackberry Tea | 0.5 | 14 | 4 | |
| Sweet Labrador Tea | 0.5 | 6 | 4 | |
| Sweet Mutfruit Tea | 0.5 | 14 | 4 | |
| Sweet Roll | 0.25 | 23 | 5 | |
| Sweet Tato Stew | 1 | 22 | 5 | |
| Sweetwater Special Blend | 0.5 | 15 | 4 | Addictive |
| Syrup | 0.5 | 12 | 4 | |
| Tales from the West Virginia Hills 1 | 0.01 | 400 | 1 | |
| Tales from the West Virginia Hills 2 | 0.01 | 400 | 1 | |
| Tales from the West Virginia Hills 3 | 0.01 | 400 | 1 | |
| Tales from the West Virginia Hills 4 | 0.01 | 400 | 1 | |
| Tales from the West Virginia Hills 5 | 0.01 | 400 | 1 | |
| Talons Serum | 0.25 | 2,000 | 2 | |
| Tarberry | 0.25 | 5 | 3 | |
| Tarberry Juice | 0.5 | 5 | 4 | |
| Tasty Mutant Hound Stew | 1 | 28 | 5 | |
| Tasty Mutton Meat Pie | 1 | 38 | 4 | |
| Tasty Radscorpion Egg Omelette | 0.25 | 40 | 4 | |
| Tasty Squirrel Stew | 1 | 16 | 5 | |
| Tasty Yao Guai Roast | 1 | 38 | 4 | |
| Tater Shine | 1.2 | 10 | 9 | Addictive |
| Tato | 0.5 | 7 | 3 | |
| Tato Flower | 0.25 | 7 | 3 | |
| Tato Juice | 0.5 | 7 | 4 | |
| Tato Salad | 1 | 6 | 4 | |
| Tato Salad Surprise | 1 | 6 | 4 | |
| Tato Soup | 0.5 | 7 | 5 | |
| Tesla Science 1 | 0.01 | 400 | 1 | |
| Tesla Science 2 | 0.01 | 0 | 1 | |
| Tesla Science 3 | 0.01 | 0 | 1 | |
| Tesla Science 4 | 0.01 | 0 | 1 | |
| Tesla Science 5 | 0.01 | 0 | 1 | |